You may notice your skin feels thinner, less elastic or harder to maintain despite good skincare. The body's own hyaluronic acid production begins to decline from the late twenties, and topical products cannot reach the deeper layers. Profhilo is a bio-remodelling injectable that targets that loss from within, stimulating the skin's own collagen, elastin and HA over a two-session course on the face, neck, décolletage and hands. At Array, every Profhilo course is led by Dr Chris Hutton inside our RQIA-regulated Belfast clinic.
Treatment with Profhilo must adhere to a strict protocol outlined by the manufacturer. For facial treatment, 5 Bio-Aesthetic Points (BAPs) are injected on each side of the face. A second treatment is carried out 4 weeks later.
Profhilo is a bio-remodelling injectable from IBSA, made from a hybrid formulation of high and low molecular weight hyaluronic acid. Unlike a traditional filler, it does not stay where it is injected. The product diffuses beneath the skin over several hours, signalling the body to produce its own collagen, elastin and hyaluronic acid in response. The standard course is two sessions four weeks apart, with the cumulative shift in tone, elasticity and hydration most visible six to eight weeks after the second session.
Profhilo is injected at five points on each side of the face using the BAP protocol (Bio Aesthetic Points), a technique developed specifically for the product. After injection, the hyaluronic acid spreads across a wide area beneath the skin rather than holding shape at the injection site. That diffusion is what triggers the bio-stimulation: fibroblasts respond to the presence of HA by producing collagen, elastin and the body's own hyaluronic acid over the weeks that follow. Each session takes around thirty minutes, with minimal recovery.
Profhilo is the right treatment when the goal is skin quality rather than volume or shape. Patients typically come to it in their thirties, forties or fifties, when hydration has dropped and the skin has lost some of its elasticity but is not yet ready for volume replacement or surgical tightening. The result is improved tone, hydration and a clearer glow, with no change to facial structure. Most patients return for a maintenance session every six to nine months once the initial course is complete.
Profhilo at Array is led by co-founder Dr Chris Hutton (GMC: 7039324), an experienced lead injector and Merz Aesthetics training partner, within a multi-doctor team co-founded with Dr Judith Storm.
Profhilo and dermal fillers are often confused. Both contain hyaluronic acid, but fillers stay where they are injected to restore volume in a specific area such as the cheeks, lips or under-eyes. Profhilo spreads to bio-remodel the skin across a wider area, improving quality without changing shape. Polynucleotides also bio-stimulate but use purified salmon DNA rather than HA. Morpheus8 and Ultherapy address skin laxity at structural depths Profhilo cannot reach.
You are a candidate for Profhilo if your skin feels less elastic and less hydrated than it used to, if fine lines have started to settle and your goal is improved skin quality rather than added volume. Your clinician will guide you to the right starting point at your assessment.
Profhilo is often built into a wider skin plan rather than treated as a standalone session. It pairs cleanly with botulinum toxin, which addresses dynamic lines that bio-remodelling does not, and with dermal fillers in patients who need volume restored in specific areas while their broader skin envelope is improved. Light-based treatments such as BBL or HALO can be sequenced for surface clarity. Your clinician will set the order and spacing of treatments at consultation, which protects healing windows and ensures each result earns its place.
Profhilo treats the early signs of skin ageing including loss of elasticity, dehydration, fine surface lines and a tired or dull appearance. It is the right treatment when overall skin quality is the primary concern. It does not treat deep wrinkles, sagging skin or loss of facial volume, which need different treatments to address properly.
The standard Profhilo protocol is delivered on the face using five injection points on each side. It is also used on the neck, décolletage and the back of the hands, areas that thin and lose elasticity earlier than the rest of the body and often give away age before the face does.
A standard Profhilo course produces measurable improvements in skin firmness, hydration and tone. The change is usually described as looking healthier rather than different, which is the intention of a bio-remodelling treatment. Results last six to nine months and can be maintained with a top-up session at the end of that window.
Each Profhilo session takes around thirty minutes. Ten injections are placed on the face, five on each side. Most patients describe them as a brief sting rather than sustained discomfort. Small raised bumps appear at each injection point immediately afterwards and settle within twenty-four hours as the hyaluronic acid diffuses out.
Profhilo is a biocompatible hyaluronic acid product with an established clinical safety profile. The most common side effects are short-lived redness, mild swelling or small bruises at the injection sites. Serious reactions are rare, which is why a clinician-led assessment is required before treatment at our RQIA-regulated Belfast clinic.
Avoid touching the treated areas for several hours and skip strenuous exercise, saunas and very hot showers for twenty-four hours. The small injection bumps settle on their own. Resume your usual skincare routine the following day including SPF, and avoid facials, lasers or other injectables for two weeks while the bio-remodelling completes.
Profhilo is a bio-remodelling injectable made from hyaluronic acid. Unlike a traditional dermal filler, it spreads through the skin after injection to stimulate the body's own collagen and elastin, improving skin elasticity, hydration and tone rather than restoring lost volume.
6 – 9 months. Results vary from patient to patient.
At Array, all patients receive follow up as required. Contact a member of our team at enquiries@arrayaesthetics.com or call 02894 571 840 to arrange your review appointment.
Profhilo is manufactured by IBSA and distributed by HA-Derma, an Italian company known for producing products of outstanding purity.
Although a little uncomfortable, patients tolerate the procedure well. The procedure is quick!
A traditional filler sits where it is placed to restore volume to a specific area. Profhilo spreads after injection to bio-remodel the skin across a wider area, improving quality, hydration and elasticity rather than shape.
The standard Profhilo course is two sessions four weeks apart. Most patients return for a single top-up session every six to nine months thereafter, although the timing varies with skin condition and lifestyle.
Results build gradually as the product stimulates collagen and elastin. Most patients see visible change four to six weeks after the second session, with refinement continuing over the following month.
Profhilo is not suitable during pregnancy or breastfeeding, on active skin infections or for patients with known hyaluronic acid sensitivity. Your clinician will review your medical history at your consultation.
Yes. Profhilo is regularly sequenced with botulinum toxin, dermal fillers or skin treatments such as BBL. Your clinician will plan the order and spacing of treatments to protect each result and avoid over-treatment.